IBS
Why your IBS is not a gut problem
The stress-gut-brain axis explains why every gastroenterologist has given you temporary relief but not resolution.
Article coming soonPhysician-supervised · Integrative · Root cause
You have been
here before.
This time
is different.
Medicine that treats the root, not the symptom. For those living with IBS, migraine, PCOS, hair fall, and lifestyle-related illness. One physician. One integrated plan. Measurable outcomes — every week.
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● Patient outcome · Week 14
"My IBS is gone. Three years, four specialists — it took a physician who treated me as a whole person, not a set of symptoms, to finally resolve it."
Qualified physicians
Medicines dispensed & delivered monthly
Weekly 5-metric outcome scoring
Teleconsultation · Pan-India
Why chronic disease persists
You were not misdiagnosed. You were treated for symptoms — not the constitutional pattern producing them. That is a different problem, requiring a different system.
3–5
doctors seen by the average Holist patient before finding lasting relief
Source: Holist patient intake data, 2024–2025
41.7%
of Indian adults carry at least one chronic condition that is managed, not resolved
Source: ICMR-INDIAB Study, 2023
84%
of Holist patients stay beyond 90 days — because they are seeing measurable change
Source: Holist platform retention data, 2024–2025
The Method
Three disciplines.
Three disciplines.
One physician.
One integrated plan.
No fragmented referrals. No separate nutritionist, therapist, and specialist operating in isolation. At Holist, one qualified physician holds all three pillars simultaneously — and tracks your progress every week.
Classical Homeopathy
Constitutional remedy targeting the systemic root cause. Individual prescription — not a condition protocol. Medicines dispatched monthly.
Personalised Dietetics
Condition-specific nutrition for Indian dietary patterns. Updated monthly from your weekly score data.
Mental Health Support
Stress tracked as clinical data — not referred elsewhere. Weekly check-in by the same physician.
Conditions we address
If allopathy manages it
If allopathy manages it
but never resolves it.
Each condition is framed the way our patients describe it — because being heard is the first step to being treated.
IBS
"My gastroenterologist told me it was stress. He wasn't wrong. But that was never the whole answer."
Chronic Migraine
"I was on prophylactics for two years. The attacks never stopped. They just became more predictable."
Hair Fall
"I tried every supplement. My levels were fine. The fall continued."
PCOS
"Three years on the pill. I came off it and everything came back — worse than before."
Stress & Burnout
"I took a holiday. Two weeks later, I was exactly where I left off."
Skin Disorders
"The cream cleared it. Then it came back. Every dermatologist had the same answer."
The clinical architecture
Not one treatment.
Not one treatment.
Four disciplines.
Classical Homeopathy
Constitutional remedy targeting the systemic root cause. Individual prescription based on your complete picture. Medicines dispatched monthly.
Personalised Dietetics
Condition-specific protocol for Indian dietary patterns. Updated at every monthly review from your score data.
Mental Health Support
Weekly psychological check-in by the same physician. Stress tracked as a clinical variable — not an afterthought.
Weekly Monitoring
5-metric score every Sunday. Symptom, stress, sleep, energy, secondary complaints. Deviation triggers intervention.
The weekly score
Progress you
Progress you
can measure.
Every Sunday your physician receives your 5-metric score. When scores drop 5+ points week-on-week, an intervention is triggered before you feel it in your body.
The score is the clinical spine of Holist — not an engagement metric.
Patient Progress — Week 12
Active
Priya S.
PCOS · Hair Fall · Fatigue
Stage 3: Correction
Symptom
39/50
Energy
36/50
Sleep
41/50
Stress
33/50
Physician: Dr. Mandar Vijay Mandlik, BHMS · Week 12 review completed
Patient outcomes
In their own words.
"After two years and four dermatologists, my hair fall has reduced by seventy percent. Dr. Mandlik treated the stress, the hormones, and the constitution simultaneously. Nothing I had tried before came close."
Score: 19 → 41 / 50 by Month 5
Sneha R.
PCOS / Hair Fall · 6 months
"My migraines dropped from twelve days a month to two. I could see the improvement in the numbers before I felt it. For the first time, I had evidence, not just hope."
Attack frequency reduced 83% by Month 4
Arjun M.
Chronic Migraine · 5 months
"Three years of IBS. Resolved in four months. I had been told it was stress-related, as if naming it was the same as treating it. Holist treated the system driving it."
Symptom-free by Month 4, sustained
Vikram K.
IBS / Burnout · 4 months
Illustrative outcomes based on representative Holist patient cases. Individual results vary. Names changed for privacy.
Ready to begin
Find out what is actually driving your condition.
First consultation includes full clinical assessment, your personalised care plan, and Month 1 medicines dispatched to your door.
Conditions we addressYour condition
Your condition
has a root cause.
We address the systemic imbalance producing your symptoms — not the symptoms at the surface.
"My gastroenterologist told me it was stress-related. He wasn't entirely wrong. But naming the cause is not the same as addressing it — and no one did."
IBS is a gut-brain-stress axis disorder. Holist addresses the nervous system dysregulation, constitutional imbalance, and stress architecture driving the condition at its root.
Common presentationsAlternating constipation & diarrhoea
Bloating & cramping
Stress-triggered flares
Urgency & frequency
Anxiety & brain fog
Incomplete evacuation
The Holist approach
01 · Classical Homeopathy
Constitutional remedy based on temperament, stress patterns, and specific digestive response. Not a generic IBS remedy — an individual prescription.
02 · Gut-Specific Dietetics
Low-FODMAP adapted to Indian dietary patterns. Systematic trigger identification. Microbiome support through dietary protocol.
03 · Stress Architecture
Weekly check-in monitors the stress-gut connection directly. Cognitive pattern review as clinical intervention.
04 · Weekly Monitoring
Bowel pattern, energy, stress, and sleep tracked weekly. Progress visible in data before felt in the body.
8–12
wks
wks
Significant symptom reliefRoot cause correction over 4–6 months for most constitutional types
"I was on prophylactics for two years. The attacks became more predictable, not less frequent. I was told this was good management. I wanted resolution."
Migraine is a neurological sensitivity disorder with hormonal, stress, and metabolic drivers. Prophylactics suppress frequency. Holist addresses all three drivers simultaneously.
Common presentationsUnilateral throbbing headache
Nausea & photophobia
Visual aura
Hormonal triggers
Post-attack fatigue
Increasing frequency
The Holist approach
01 · Constitutional Remedy
Prescription depends on laterality, triggers, aura nature, and the complete neurological picture. Precision matters.
02 · Trigger-Elimination Diet
Systematic dietary trigger identification. Caffeine tapering, tyramine management, hormonal food influences addressed.
03 · Stress Sensitisation
Stress is the largest migraine amplifier. Weekly monitoring tracks nervous system state and cortisol load as clinical variables.
50–70%
Reduction in attack frequencyBy Week 12–16 for most constitutional types
"Every test came back normal. My ferritin, thyroid, vitamins — all fine. The dermatologist prescribed minoxidil. The fall continued."
Chronic hair fall is almost always multifactorial — stress, hormonal imbalance, nutritional deficiency, and genetic predisposition acting simultaneously. Treating one factor produces temporary results at best.
Common presentationsDiffuse thinning
Increased daily fall
Receding hairline
Scalp sensitivity
Associated PCOS / thyroid
Stress-triggered worsening
The Holist approach
01 · Constitutional Homeopathy
Remedies targeting hormonal, stress-related, or constitutional factors driving follicle miniaturisation. Systemic correction.
02 · Hair-Specific Nutrition
Iron, zinc, biotin, and protein optimisation. Indian diet-adapted protocol addressing deficiencies amplifying genetic susceptibility.
03 · Cortisol Protocol
Telogen effluvium is the most common and most reversible form of hair fall. Addressed directly through the mental health pillar.
12–16
wks
wks
Reduction in fall, initial regrowthVisible progress in most constitutional types
"I was on the pill for three years. I came off it and everything came back worse than before. My gynaecologist said this was expected."
PCOS is a hormonal disorder with metabolic, psychological, and systemic dimensions. OCPs suppress the symptoms. Holist addresses the hormonal dysregulation at its constitutional root.
Common presentationsIrregular cycles
Hair fall & facial hair
Acne & oily skin
Weight gain
Mood changes & anxiety
Difficulty conceiving
The Holist approach
01 · Hormonal Regulation
Constitutional remedies for the specific hormonal pattern — an individual treatment plan, not a PCOS protocol.
02 · Insulin-Sensitising Diet
Low-glycaemic, anti-inflammatory approach for Indian dietary patterns. Inositol support integrated into the monthly care plan.
03 · HPA Axis & Cortisol
HPA axis dysregulation is a primary PCOS driver. Stress tracked weekly as a clinical data point — not advised generically.
3–5
mo
mo
Measurable hormonal improvementMenstrual regulation and energy restoration visible in score data
"I took two weeks off and came back exactly where I left. Everyone said I needed more rest. Rest doesn't fix what rest didn't cause."
Burnout is a physiological state — HPA axis dysregulation, adrenal exhaustion, nervous system overload. Supplements do not correct it. Holist addresses the underlying system.
Common presentationsFatigue despite sleep
Cognitive fog
Emotional numbness
Physical tension
Digestive worsening under stress
Loss of motivation
The Holist approach
01 · Nervine Homeopathy
Constitutional remedies for nervous system exhaustion — selected for the specific burnout pattern, not a generic stress remedy.
02 · Adrenal Nutrition
Magnesium, B-complex, and adaptogenic support through diet. Anti-inflammatory protocol to reduce systemic inflammatory load.
03 · HPA Axis Monitoring
Weekly analysis of stress load, recovery patterns, and sleep architecture. Practical interventions — not generic lifestyle advice.
6–10
wks
wks
Energy and sleep scores improve firstEarliest indicators of HPA axis recovery visible in weekly data
"The steroid cream cleared it. Then it came back. My dermatologist prescribed a stronger version. This cycle has been going on for four years."
Eczema, psoriasis, and adult acne are immune-gut-skin axis disorders. Topical treatment suppresses the flare. Holist addresses the immune dysregulation and constitutional susceptibility driving recurrence.
Common presentationsRecurring eczema flares
Psoriatic plaques
Adult acne
Stress-triggered worsening
Gut symptoms alongside flares
Steroid-dependent cycles
The Holist approach
01 · Constitutional Treatment
Deep-acting remedies addressing immune dysregulation and constitutional background — systemic correction, not topical palliation.
02 · Gut-Skin Axis Diet
Anti-inflammatory protocol targeting gut permeability — the primary driver of immune overactivation in chronic skin disorders.
03 · Stress & Flare Patterns
Stress is the most common acute flare trigger. Clinical monitoring of stress load is integral to the skin treatment plan.
10–16
wks
wks
Flare frequency reductionSkin barrier improvement and reduced steroid dependency
The processFive stages.
Five stages.
One physician throughout.
A structured journey from first consultation to sustained recovery. Measurable milestones at every step.
First Consultation
Full 4-pillar intake
Complete clinical intake (60 min). Constitutional homeopathic assessment. Dietetics protocol drafted. Psychological baseline established. Month 1 medicines dispatched. Weekly scoring activated.
Day 1 · ₹2,999
Stabilisation
Baseline establishment
Baseline scores set across all 5 metrics. Constitutional remedy initiated at correct potency. Dietary protocol begins. Foundation is being laid — no dramatic changes expected yet.
Weeks 1–4
Regulation
First measurable shifts
Energy and sleep scores improve first — earliest indicators of constitutional response. Primary symptoms begin responding. Remedy potency adjusted from score data.
Months 2–3
Correction
Root cause addressed
Hormonal, metabolic, or systemic patterns shift at constitutional level. Significant measurable change visible in score trajectory. Intercurrent remedies introduced if indicated.
Months 3–5
Maintenance
Self-managed recovery
Improvements stabilised. Remedy frequency reduced. Patient self-managing with quarterly check-ins. Medicines used situationally. Long-term health relationship established.
Month 6+
Four pillars in depth
Not one treatment.
Not one treatment.
Four disciplines. One plan.
01 / Homeopathy
Classical Homeopathy
Constitutional remedy selected on the complete patient — temperament, stress patterns, physical symptoms, modalities. Not a protocol. An individual prescription that evolves at every monthly review.
Medicines dispensed by the physician and dispatched monthly.
Potency and repetition adjusted from weekly score data — not at fixed intervals.
02 / Dietetics
Personalised Dietetics
Condition-specific nutrition protocol designed for Indian dietary patterns. Not a generic diet sheet — a living plan adjusted at every monthly review from score trajectory.
Encompasses gut, hormonal, anti-inflammatory, and adrenal nutritional frameworks as indicated by your condition.
Dietary protocol updated at every monthly review — not issued once and forgotten.
03 / Psychology
Mental Health Support
Weekly psychological check-in by the same physician — not a referral. Stress load, coping architecture, and emotional wellbeing tracked as clinical data points in the weekly score.
The stress-disease connection is the most underaddressed component of chronic illness management. At Holist it is a primary clinical variable.
Mental health score is one of the five tracked metrics — not an afterthought.
04 / Monitoring
Weekly Outcome Monitoring
5-metric score submitted every Sunday. Symptom severity, stress load, sleep quality, energy level, and secondary complaints tracked longitudinally across the full treatment period.
When scores drop 5+ points week-on-week, an intervention is triggered. Progress is visible in the data before it is felt in the body.
The weekly score is the clinical spine of Holist — not an engagement metric.
Start your journey
Ready to begin your assessment?
First consultation includes full clinical assessment, personalised care plan, and Month 1 medicines dispatched.
Transparent pricingEverything included.
Everything included.
No surprises.
Medicines, supplements, consultation, and monitoring — one transparent monthly fee.
First Consultation
₹2,999
One-time · 60 minutes · All pillars assessed
- Full clinical intake across all 4 pillars
- Constitutional homeopathic assessment
- Personalised dietetics protocol drafted
- Psychological baseline assessment
- Month 1 medicines + supplements dispatched
- Weekly scoring system activated
- Full care plan document shared
- Patient record created
Monthly Supervision
₹2,999
Per month · Ongoing · Cancel anytime
- Monthly review consultation (30–45 min)
- Remedy review and potency adjustment
- Dietetics protocol updated from score data
- Mental health check-in
- Medicines + supplements dispatched
- Weekly score review and clinical notes
- Healing stage progression assessment
- Physician access for red-flag queries
What's included
Medicines and supplements included in your monthly fee. No hidden costs.
Our missionRoot cause medicine,
Root cause medicine,
at scale.
India's chronic care gap is not a shortage of patients or physicians — it is a shortage of systems designed to treat the whole person.
Why Holist exists
41.7% of Indian adults carry a chronic condition.
Most have seen 3–5 specialists. Most have been given indefinite medication. Most have been told their condition is manageable but not resolvable. Holist was built to prove that wrong.
The four-pillar framework — homeopathy, dietetics, mental health support, and weekly monitoring — treats the constitutional root rather than the presenting symptom. The weekly score makes improvement undeniable.
84%
90-day patient retention
3–5
Avg. prior doctors seen
₹2,999
All-inclusive monthly fee
Our values
What Holist stands for.
Outcomes over impressions
We track 5 metrics every week because what we can measure we can improve. Clinical data over subjective satisfaction.
Root cause over symptom management
We treat the constitutional pattern producing your condition — not the surface symptoms your previous physicians addressed.
Integration over referral
One physician holds all four pillars simultaneously. No fragmentation. No lost context between providers.
Framework over intuition
The 5-stage healing architecture and weekly scoring system are clinical instruments — not wellness frameworks.
Transparency over mystique
We publish our cost structure. We share our clinical framework. We show you the data behind every decision.
Sustainability over speed
Chronic disease took years to develop. Resolution takes months. We are not a quick-fix platform.
The physician
Meet Dr. Mandar Vijay Mandlik.
Dr. Mandlik is the founder and chief physician of Holist. He designed the four-pillar clinical framework, the five-stage healing architecture, and the outcome-tracking protocols used in every patient case.
Holist is built on the principle that chronic disease requires longitudinal, integrated supervision — not episodic prescription. Every patient is treated as a clinical data set and a human being simultaneously.
Qualification
BHMS — Bachelor of Homeopathic Medicine & Surgery
Specialisation
Chronic lifestyle, skin, hair & hormonal disorders
Clinical Method
Classical constitutional homeopathy integrated with dietetics & psychological support
Tracking System
5-metric weekly score — symptom, stress, sleep, energy, secondary complaints
Framework
5-Stage Healing Architecture — Stabilisation through Maintenance
Format
Teleconsultation — pan-India patients
Clinical insights
The Holist Journal.
Physician-authored content on root cause medicine and integrative health — for educated, skeptical patients.
Migraine
The hormonal migraine nobody told you about
If your migraines worsen around your cycle, you are not imagining it. The oestrogen-withdrawal trigger is one of the most treatable causes.
Article coming soon
Hair Fall
Why your hair fall supplement is not working
Iron, biotin, and zinc are necessary but not sufficient. The constitutional factors driving follicle miniaturisation are not addressable by supplementation alone.
Article coming soon
PCOS
Why going off birth control makes PCOS worse
The rebound effect is real, predictable, and preventable. Here is what happens hormonally when you stop OCPs.
Article coming soon
Burnout
The HPA axis: why you are exhausted even after a holiday
Adrenal fatigue is not a myth. It is a pattern of HPA axis dysregulation that no amount of rest alone resolves.
Article coming soon
Methodology
Why we track your progress weekly
Most platforms track engagement. Holist tracks clinical outcomes. Here is why the 5-metric score is the most important part of your care plan.
Article coming soonStep 01 of 03
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Step 02 of 03
What brings you to Holist?
This allows your physician to review your case before your consultation begins.
Step 03 of 03
Confirm & complete.
Review your details and complete payment to confirm your consultation.
Order Summary₹2,999
First Consultation (60 min)₹1,000
Medicines + Supplements (Month 1)₹1,500
Packaging + Courier₹140
Payment Gateway Fee₹60
Platform Overhead₹299
Total₹2,999
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